Cargando…

Pasteurella multocida Bacteremia in a Patient With Ovarian Cancer and Chemotherapy-induced Neutropenia

Background: Pasteurella multocida is a commensal organism found in the saliva and oropharynx of domestic animals. It causes a variety of human infections ranging from cellulitis to bacteremia and sepsis. The severity of infection is somewhat related to the immunocompetency of the infected host. An i...

Descripción completa

Detalles Bibliográficos
Autores principales: Casey, A. Catherine, Greenspoon, Jeffrey S., Lagasse, Leo D.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1995
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366153/
https://www.ncbi.nlm.nih.gov/pubmed/18472893
http://dx.doi.org/10.1155/S1064744995000639
_version_ 1782154266784301056
author Casey, A. Catherine
Greenspoon, Jeffrey S.
Lagasse, Leo D.
author_facet Casey, A. Catherine
Greenspoon, Jeffrey S.
Lagasse, Leo D.
author_sort Casey, A. Catherine
collection PubMed
description Background: Pasteurella multocida is a commensal organism found in the saliva and oropharynx of domestic animals. It causes a variety of human infections ranging from cellulitis to bacteremia and sepsis. The severity of infection is somewhat related to the immunocompetency of the infected host. An immunocompromised host is more likely to suffer a disseminated infection as a result of contact with this organism than an immunocompetent host. This case report and review of the literature are presented to further evaluate the types of infections caused by this organism in oncology patients. Case: A 54-year-old woman with epithelial ovarian cancer and a chemotherapy-induced nadir of her WBC count developed P. multocida bacteremia after she incurred a scratch from her pet cat. She was treated with ceftazidime and then penicillin G with prompt resolution of the bacteremia. Conclusion: This paper summarizes an infectious complication that is likely to become more common as chemotherapy-induced neutropenia and pet ownership in the elderly become common coincidences. As such, oncologists and infectious disease physicians should keep this organism in mind when selecting antibiotics to treat the febrile, nadiring cancer patient who has known pet contact.
format Text
id pubmed-2366153
institution National Center for Biotechnology Information
language English
publishDate 1995
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-23661532008-05-12 Pasteurella multocida Bacteremia in a Patient With Ovarian Cancer and Chemotherapy-induced Neutropenia Casey, A. Catherine Greenspoon, Jeffrey S. Lagasse, Leo D. Infect Dis Obstet Gynecol Research Article Background: Pasteurella multocida is a commensal organism found in the saliva and oropharynx of domestic animals. It causes a variety of human infections ranging from cellulitis to bacteremia and sepsis. The severity of infection is somewhat related to the immunocompetency of the infected host. An immunocompromised host is more likely to suffer a disseminated infection as a result of contact with this organism than an immunocompetent host. This case report and review of the literature are presented to further evaluate the types of infections caused by this organism in oncology patients. Case: A 54-year-old woman with epithelial ovarian cancer and a chemotherapy-induced nadir of her WBC count developed P. multocida bacteremia after she incurred a scratch from her pet cat. She was treated with ceftazidime and then penicillin G with prompt resolution of the bacteremia. Conclusion: This paper summarizes an infectious complication that is likely to become more common as chemotherapy-induced neutropenia and pet ownership in the elderly become common coincidences. As such, oncologists and infectious disease physicians should keep this organism in mind when selecting antibiotics to treat the febrile, nadiring cancer patient who has known pet contact. Hindawi Publishing Corporation 1995 /pmc/articles/PMC2366153/ /pubmed/18472893 http://dx.doi.org/10.1155/S1064744995000639 Text en Copyright © 1995 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Casey, A. Catherine
Greenspoon, Jeffrey S.
Lagasse, Leo D.
Pasteurella multocida Bacteremia in a Patient With Ovarian Cancer and Chemotherapy-induced Neutropenia
title Pasteurella multocida Bacteremia in a Patient With Ovarian Cancer and Chemotherapy-induced Neutropenia
title_full Pasteurella multocida Bacteremia in a Patient With Ovarian Cancer and Chemotherapy-induced Neutropenia
title_fullStr Pasteurella multocida Bacteremia in a Patient With Ovarian Cancer and Chemotherapy-induced Neutropenia
title_full_unstemmed Pasteurella multocida Bacteremia in a Patient With Ovarian Cancer and Chemotherapy-induced Neutropenia
title_short Pasteurella multocida Bacteremia in a Patient With Ovarian Cancer and Chemotherapy-induced Neutropenia
title_sort pasteurella multocida bacteremia in a patient with ovarian cancer and chemotherapy-induced neutropenia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366153/
https://www.ncbi.nlm.nih.gov/pubmed/18472893
http://dx.doi.org/10.1155/S1064744995000639
work_keys_str_mv AT caseyacatherine pasteurellamultocidabacteremiainapatientwithovariancancerandchemotherapyinducedneutropenia
AT greenspoonjeffreys pasteurellamultocidabacteremiainapatientwithovariancancerandchemotherapyinducedneutropenia
AT lagasseleod pasteurellamultocidabacteremiainapatientwithovariancancerandchemotherapyinducedneutropenia