Ferrocene-Derived Pyrazinoyl and Nicotinoyl Schiff-Bases: Their Synthesis, Characterization and Biological Properties

A novel class of acetylferrocene-derived Schiff-bases such as 2-pyrazinoyl-1-(2-ferroceneylmethylene)- hydrazide (HL(1)) and 2-nicotinoyl-1-(2-ferrocenylmethylene)hydrazide (HL(2)) have been synthesized and characterized by their IR, (1)H NMR, (13)C NMR and microanalytical date. The biological effec...

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Detalles Bibliográficos
Autores principales: Chohan, Zahid H., Praveen, M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1999
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366828/
https://www.ncbi.nlm.nih.gov/pubmed/18472904
http://dx.doi.org/10.1155/MBD.1999.149
Descripción
Sumario:A novel class of acetylferrocene-derived Schiff-bases such as 2-pyrazinoyl-1-(2-ferroceneylmethylene)- hydrazide (HL(1)) and 2-nicotinoyl-1-(2-ferrocenylmethylene)hydrazide (HL(2)) have been synthesized and characterized by their IR, (1)H NMR, (13)C NMR and microanalytical date. The biological effect induced due to the coupling of ferrocene molecule with the aroylhydrazines e.g., pyrazinoylhydrazine and nicotinoylhydrazine has been studied against bacterial species such as Escherichia coli, Pseudomonas aeruginosa , Staphylococcus aureus and Klebsiella pneumonae.

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