Ferrocene-Derived Pyrazinoyl and Nicotinoyl Schiff-Bases: Their Synthesis, Characterization and Biological Properties

A novel class of acetylferrocene-derived Schiff-bases such as 2-pyrazinoyl-1-(2-ferroceneylmethylene)- hydrazide (HL(1)) and 2-nicotinoyl-1-(2-ferrocenylmethylene)hydrazide (HL(2)) have been synthesized and characterized by their IR, (1)H NMR, (13)C NMR and microanalytical date. The biological effec...

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Detalles Bibliográficos
Autores principales: Chohan, Zahid H., Praveen, M.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1999
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366828/
https://www.ncbi.nlm.nih.gov/pubmed/18472904
http://dx.doi.org/10.1155/MBD.1999.149
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author Chohan, Zahid H.
Praveen, M.
author_facet Chohan, Zahid H.
Praveen, M.
author_sort Chohan, Zahid H.
collection PubMed
description A novel class of acetylferrocene-derived Schiff-bases such as 2-pyrazinoyl-1-(2-ferroceneylmethylene)- hydrazide (HL(1)) and 2-nicotinoyl-1-(2-ferrocenylmethylene)hydrazide (HL(2)) have been synthesized and characterized by their IR, (1)H NMR, (13)C NMR and microanalytical date. The biological effect induced due to the coupling of ferrocene molecule with the aroylhydrazines e.g., pyrazinoylhydrazine and nicotinoylhydrazine has been studied against bacterial species such as Escherichia coli, Pseudomonas aeruginosa , Staphylococcus aureus and Klebsiella pneumonae.
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spelling pubmed-23668282008-05-12 Ferrocene-Derived Pyrazinoyl and Nicotinoyl Schiff-Bases: Their Synthesis, Characterization and Biological Properties Chohan, Zahid H. Praveen, M. Met Based Drugs Research Article A novel class of acetylferrocene-derived Schiff-bases such as 2-pyrazinoyl-1-(2-ferroceneylmethylene)- hydrazide (HL(1)) and 2-nicotinoyl-1-(2-ferrocenylmethylene)hydrazide (HL(2)) have been synthesized and characterized by their IR, (1)H NMR, (13)C NMR and microanalytical date. The biological effect induced due to the coupling of ferrocene molecule with the aroylhydrazines e.g., pyrazinoylhydrazine and nicotinoylhydrazine has been studied against bacterial species such as Escherichia coli, Pseudomonas aeruginosa , Staphylococcus aureus and Klebsiella pneumonae. Hindawi Publishing Corporation 1999 /pmc/articles/PMC2366828/ /pubmed/18472904 http://dx.doi.org/10.1155/MBD.1999.149 Text en Copyright © 1999 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Chohan, Zahid H.
Praveen, M.
Ferrocene-Derived Pyrazinoyl and Nicotinoyl Schiff-Bases: Their Synthesis, Characterization and Biological Properties
title Ferrocene-Derived Pyrazinoyl and Nicotinoyl Schiff-Bases: Their Synthesis, Characterization and Biological Properties
title_full Ferrocene-Derived Pyrazinoyl and Nicotinoyl Schiff-Bases: Their Synthesis, Characterization and Biological Properties
title_fullStr Ferrocene-Derived Pyrazinoyl and Nicotinoyl Schiff-Bases: Their Synthesis, Characterization and Biological Properties
title_full_unstemmed Ferrocene-Derived Pyrazinoyl and Nicotinoyl Schiff-Bases: Their Synthesis, Characterization and Biological Properties
title_short Ferrocene-Derived Pyrazinoyl and Nicotinoyl Schiff-Bases: Their Synthesis, Characterization and Biological Properties
title_sort ferrocene-derived pyrazinoyl and nicotinoyl schiff-bases: their synthesis, characterization and biological properties
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2366828/
https://www.ncbi.nlm.nih.gov/pubmed/18472904
http://dx.doi.org/10.1155/MBD.1999.149
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AT praveenm ferrocenederivedpyrazinoylandnicotinoylschiffbasestheirsynthesischaracterizationandbiologicalproperties

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