Cytokine Production by Human Colonic Intraepithelial Lymphocytes in Controls and Ulcerative Colitis

Using an ELISA technique, concentrations of γ-interferon and interleukin-2 were assayed in the supernatants of colonic intraepithelial lymphocytes cultured with or without phytohaemagglutinin (PHA). IntraepitheHal lymphocytes produced low concentrations of γ-interferon and interleukin-2 when stimula...

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Detalles Bibliográficos
Autores principales: Hoang, P., Dalton, H. R., de Silv, H. J., Jewell, D. P.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367034/
https://www.ncbi.nlm.nih.gov/pubmed/18472946
http://dx.doi.org/10.1155/S0962935194000311
Descripción
Sumario:Using an ELISA technique, concentrations of γ-interferon and interleukin-2 were assayed in the supernatants of colonic intraepithelial lymphocytes cultured with or without phytohaemagglutinin (PHA). IntraepitheHal lymphocytes produced low concentrations of γ-interferon and interleukin-2 when stimulated with PHA, but significantly more than when unstimulated (p < 0.05). There was no difference in production of these cytokines by IEL from control or inflammatory bowel disease.

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