Cytokine Production by Human Colonic Intraepithelial Lymphocytes in Controls and Ulcerative Colitis

Using an ELISA technique, concentrations of γ-interferon and interleukin-2 were assayed in the supernatants of colonic intraepithelial lymphocytes cultured with or without phytohaemagglutinin (PHA). IntraepitheHal lymphocytes produced low concentrations of γ-interferon and interleukin-2 when stimula...

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Detalles Bibliográficos
Autores principales: Hoang, P., Dalton, H. R., de Silv, H. J., Jewell, D. P.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1994
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367034/
https://www.ncbi.nlm.nih.gov/pubmed/18472946
http://dx.doi.org/10.1155/S0962935194000311
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author Hoang, P.
Dalton, H. R.
de Silv, H. J.
Jewell, D. P.
author_facet Hoang, P.
Dalton, H. R.
de Silv, H. J.
Jewell, D. P.
author_sort Hoang, P.
collection PubMed
description Using an ELISA technique, concentrations of γ-interferon and interleukin-2 were assayed in the supernatants of colonic intraepithelial lymphocytes cultured with or without phytohaemagglutinin (PHA). IntraepitheHal lymphocytes produced low concentrations of γ-interferon and interleukin-2 when stimulated with PHA, but significantly more than when unstimulated (p < 0.05). There was no difference in production of these cytokines by IEL from control or inflammatory bowel disease.
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spelling pubmed-23670342008-05-12 Cytokine Production by Human Colonic Intraepithelial Lymphocytes in Controls and Ulcerative Colitis Hoang, P. Dalton, H. R. de Silv, H. J. Jewell, D. P. Mediators Inflamm Research Article Using an ELISA technique, concentrations of γ-interferon and interleukin-2 were assayed in the supernatants of colonic intraepithelial lymphocytes cultured with or without phytohaemagglutinin (PHA). IntraepitheHal lymphocytes produced low concentrations of γ-interferon and interleukin-2 when stimulated with PHA, but significantly more than when unstimulated (p < 0.05). There was no difference in production of these cytokines by IEL from control or inflammatory bowel disease. Hindawi Publishing Corporation 1994 /pmc/articles/PMC2367034/ /pubmed/18472946 http://dx.doi.org/10.1155/S0962935194000311 Text en Copyright © 1994 Hindawi Publishing Corporation. http://creativecommons.org/licenses/by/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Hoang, P.
Dalton, H. R.
de Silv, H. J.
Jewell, D. P.
Cytokine Production by Human Colonic Intraepithelial Lymphocytes in Controls and Ulcerative Colitis
title Cytokine Production by Human Colonic Intraepithelial Lymphocytes in Controls and Ulcerative Colitis
title_full Cytokine Production by Human Colonic Intraepithelial Lymphocytes in Controls and Ulcerative Colitis
title_fullStr Cytokine Production by Human Colonic Intraepithelial Lymphocytes in Controls and Ulcerative Colitis
title_full_unstemmed Cytokine Production by Human Colonic Intraepithelial Lymphocytes in Controls and Ulcerative Colitis
title_short Cytokine Production by Human Colonic Intraepithelial Lymphocytes in Controls and Ulcerative Colitis
title_sort cytokine production by human colonic intraepithelial lymphocytes in controls and ulcerative colitis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367034/
https://www.ncbi.nlm.nih.gov/pubmed/18472946
http://dx.doi.org/10.1155/S0962935194000311
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