A mixture model approach to multiple testing for the genetic analysis of gene expression

With the availability of very dense genome-wide maps of markers, multiple testing has become a major difficulty for genetic studies. In this context, the false-discovery rate (FDR) and related criteria are widely used. Here, we propose a finite mixture model to estimate the local FDR (lFDR), the FDR...

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Detalles Bibliográficos
Autores principales: Dalmasso, Cyril, Pickrell, Joseph, Tuefferd, Marianne, Génin, Emmanuelle, Bourgain, Catherine, Broët, Philippe
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367480/
https://www.ncbi.nlm.nih.gov/pubmed/18466485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367480/
https://www.ncbi.nlm.nih.gov/pubmed/18466485

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