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Conditional genotype analysis: detecting secondary disease loci in linkage disequilibrium with a primary disease locus

A number of autoimmune and other diseases have well established HLA associations; in many cases there is strong evidence for the direct involvement of the HLA class II peptide-presenting antigens, e.g., HLA DR-DQ for type 1 diabetes (T1D) and HLA-DR for rheumatoid arthritis (RA). The involvement of...

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Detalles Bibliográficos
Autores principales: Thomson, Glenys, Valdes, Ana Maria
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367484/
https://www.ncbi.nlm.nih.gov/pubmed/18466509