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Power of the 2-locus TDT for testing the interaction of two susceptibility genes

We recently proposed a new strategy: 2-locus TDT for detecting two susceptibility genes through their interaction in trio families. We apply our method to two candidate genes, A and C, on the Genetic Analysis Workshop 15 (GAW15) simulated rheumatoid arthritis data and study the power to identify an...

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Detalles Bibliográficos
Autores principales: Kotti, Salma, Bourgey, Mathieu, Clerget-Darpoux, Françoise
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367511/
https://www.ncbi.nlm.nih.gov/pubmed/18466566

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