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Comparison of affected sibling-pair linkage methods to identify gene × gene interaction in GAW15 simulated data
Non-parametric linkage methods have had limited success in detecting gene by gene interactions. Using affected sibling-pair (ASP) data from all replicates of the simulated data from Problem 3, we assessed the statistical power of three approaches to identify the gene × gene interaction between two l...
Autores principales: | Larkin, Emma K, Morris, Nathan J, Li, Yali, Nock, Nora L, Stein, Catherine M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367530/ https://www.ncbi.nlm.nih.gov/pubmed/18466567 |
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