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Impact of normalization and filtering on linkage analysis of gene expression data
Using the Problem 1 data set made available for Genetic Analysis Workshop 15, we assessed sensitivity of linkage results to a correlation-based feature extraction method as well as to different normalization procedures applied to the raw Affymetrix gene expression microarray data. The impact of thes...
Autores principales: | Beyene, Joseph, Hu, Pingzhao, Parkhomenko, Elena, Tritchler, David |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367572/ https://www.ncbi.nlm.nih.gov/pubmed/18466495 |
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