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Impact of normalization and filtering on linkage analysis of gene expression data

Using the Problem 1 data set made available for Genetic Analysis Workshop 15, we assessed sensitivity of linkage results to a correlation-based feature extraction method as well as to different normalization procedures applied to the raw Affymetrix gene expression microarray data. The impact of thes...

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Detalles Bibliográficos
Autores principales: Beyene, Joseph, Hu, Pingzhao, Parkhomenko, Elena, Tritchler, David
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367572/
https://www.ncbi.nlm.nih.gov/pubmed/18466495

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