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GraphFind: enhancing graph searching by low support data mining techniques

BACKGROUND: Biomedical and chemical databases are large and rapidly growing in size. Graphs naturally model such kinds of data. To fully exploit the wealth of information in these graph databases, a key role is played by systems that search for all exact or approximate occurrences of a query graph....

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Detalles Bibliográficos
Autores principales: Ferro, Alfredo, Giugno, Rosalba, Mongiovì, Misael, Pulvirenti, Alfredo, Skripin, Dmitry, Shasha, Dennis
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367637/
https://www.ncbi.nlm.nih.gov/pubmed/18460171
http://dx.doi.org/10.1186/1471-2105-9-S4-S10
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author Ferro, Alfredo
Giugno, Rosalba
Mongiovì, Misael
Pulvirenti, Alfredo
Skripin, Dmitry
Shasha, Dennis
author_facet Ferro, Alfredo
Giugno, Rosalba
Mongiovì, Misael
Pulvirenti, Alfredo
Skripin, Dmitry
Shasha, Dennis
author_sort Ferro, Alfredo
collection PubMed
description BACKGROUND: Biomedical and chemical databases are large and rapidly growing in size. Graphs naturally model such kinds of data. To fully exploit the wealth of information in these graph databases, a key role is played by systems that search for all exact or approximate occurrences of a query graph. To deal efficiently with graph searching, advanced methods for indexing, representation and matching of graphs have been proposed. RESULTS: This paper presents GraphFind. The system implements efficient graph searching algorithms together with advanced filtering techniques that allow approximate search. It allows users to select candidate subgraphs rather than entire graphs. It implements an effective data storage based also on low-support data mining. CONCLUSIONS: GraphFind is compared with Frowns, GraphGrep and gIndex. Experiments show that GraphFind outperforms the compared systems on a very large collection of small graphs. The proposed low-support mining technique which applies to any searching system also allows a significant index space reduction.
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spelling pubmed-23676372008-05-07 GraphFind: enhancing graph searching by low support data mining techniques Ferro, Alfredo Giugno, Rosalba Mongiovì, Misael Pulvirenti, Alfredo Skripin, Dmitry Shasha, Dennis BMC Bioinformatics Research BACKGROUND: Biomedical and chemical databases are large and rapidly growing in size. Graphs naturally model such kinds of data. To fully exploit the wealth of information in these graph databases, a key role is played by systems that search for all exact or approximate occurrences of a query graph. To deal efficiently with graph searching, advanced methods for indexing, representation and matching of graphs have been proposed. RESULTS: This paper presents GraphFind. The system implements efficient graph searching algorithms together with advanced filtering techniques that allow approximate search. It allows users to select candidate subgraphs rather than entire graphs. It implements an effective data storage based also on low-support data mining. CONCLUSIONS: GraphFind is compared with Frowns, GraphGrep and gIndex. Experiments show that GraphFind outperforms the compared systems on a very large collection of small graphs. The proposed low-support mining technique which applies to any searching system also allows a significant index space reduction. BioMed Central 2008-04-25 /pmc/articles/PMC2367637/ /pubmed/18460171 http://dx.doi.org/10.1186/1471-2105-9-S4-S10 Text en Copyright © 2008 Ferro et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research
Ferro, Alfredo
Giugno, Rosalba
Mongiovì, Misael
Pulvirenti, Alfredo
Skripin, Dmitry
Shasha, Dennis
GraphFind: enhancing graph searching by low support data mining techniques
title GraphFind: enhancing graph searching by low support data mining techniques
title_full GraphFind: enhancing graph searching by low support data mining techniques
title_fullStr GraphFind: enhancing graph searching by low support data mining techniques
title_full_unstemmed GraphFind: enhancing graph searching by low support data mining techniques
title_short GraphFind: enhancing graph searching by low support data mining techniques
title_sort graphfind: enhancing graph searching by low support data mining techniques
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367637/
https://www.ncbi.nlm.nih.gov/pubmed/18460171
http://dx.doi.org/10.1186/1471-2105-9-S4-S10
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