Formyl-methionyl-leucyl-phenylalanine–Induced Dopaminergic Neurotoxicity via Microglial Activation: A Mediator between Peripheral Infection and Neurodegeneration?

BACKGROUND: Parkinson disease (PD), a chronic neurodegenerative disease, has been proposed to be a multifactorial disorder resulting from a combination of environmental mechanisms (chemical, infectious, and traumatic), aging, and genetic deficits. Microglial activation is important in the pathogenes...

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Detalles Bibliográficos
Autores principales: Gao, Xi, Hu, Xiaoming, Qian, Li, Yang, Sufen, Zhang, Wei, Zhang, Dan, Wu, Xuefei, Fraser, Alison, Wilson, Belinda, Flood, Patrick M, Block, Michelle, Hong, Jau-Shyong
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367670/
https://www.ncbi.nlm.nih.gov/pubmed/18470306
http://dx.doi.org/10.1289/ehp.11031

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