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Interrelation of inflammation and APP in sIBM: IL-1β induces accumulation of β-amyloid in skeletal muscle
Distinct interrelationships between inflammation and β-amyloid-associated degeneration, the two major hallmarks of the skeletal muscle pathology in sporadic inclusion body myositis (sIBM), have remained elusive. Expression of markers relevant for these pathomechanisms were analysed in biopsies of sI...
Autores principales: | Schmidt, Jens, Barthel, Konstanze, Wrede, Arne, Salajegheh, Mohammad, Bähr, Mathias, Dalakas, Marinos C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367696/ https://www.ncbi.nlm.nih.gov/pubmed/18420712 http://dx.doi.org/10.1093/brain/awn053 |
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