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Nucleocapsid mutations turn HIV-1 into a DNA-containing virus

Retroviruses replicate by converting their positive sense genomic RNA into double-stranded DNA that is subsequently integrated into the host genome. This conversion is catalyzed by reverse transcriptase (RT) early after virus entry into the target cell and is chaperoned by the nucleocapsid protein (...

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Detalles Bibliográficos
Autores principales: Houzet, Laurent, Morichaud, Zakia, Didierlaurent, Ludovic, Muriaux, Delphine, Darlix, Jean-Luc, Mougel, Marylène
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2367716/
https://www.ncbi.nlm.nih.gov/pubmed/18296486
http://dx.doi.org/10.1093/nar/gkn069