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Huntingtin-interacting protein 14, a palmitoyl transferase required for exocytosis and targeting of CSP to synaptic vesicles
Posttranslational modification through palmitoylation regulates protein localization and function. In this study, we identify a role for the Drosophila melanogaster palmitoyl transferase Huntingtin-interacting protein 14 (HIP14) in neurotransmitter release. hip14 mutants show exocytic defects at low...
Autores principales: | Ohyama, Tomoko, Verstreken, Patrik, Ly, Cindy V., Rosenmund, Tanja, Rajan, Akhila, Tien, An-Chi, Haueter, Claire, Schulze, Karen L., Bellen, Hugo J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373489/ https://www.ncbi.nlm.nih.gov/pubmed/18158335 http://dx.doi.org/10.1083/jcb.200710061 |
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