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Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement
Directional cell movement in response to external chemical gradients requires establishment of front–rear asymmetry, which distinguishes an up-gradient protrusive leading edge, where Rac-induced F-actin polymerization takes place, and a down-gradient retractile tail (uropod in leukocytes), where Rho...
Autores principales: | Lacalle, Rosa Ana, Peregil, Rosa M., Albar, Juan Pablo, Merino, Ernesto, Martínez-A, Carlos, Mérida, Isabel, Mañes, Santos |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373511/ https://www.ncbi.nlm.nih.gov/pubmed/18158329 http://dx.doi.org/10.1083/jcb.200705044 |
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