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PR-Set7–dependent lysine methylation ensures genome replication and stability through S phase
PR-Set7/SET8 is a histone H4–lysine 20 methyltransferase required for normal cell proliferation. However, the exact functions of this enzyme remain to be determined. In this study, we show that human PR-Set7 functions during S phase to regulate cellular proliferation. PR-Set7 associates with replica...
Autores principales: | Tardat, Mathieu, Murr, Rabih, Herceg, Zdenko, Sardet, Claude, Julien, Eric |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373513/ https://www.ncbi.nlm.nih.gov/pubmed/18158331 http://dx.doi.org/10.1083/jcb.200706179 |
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