Amplification and Over-Expression of the MDM2 Gene in Human Soft Tissue Tumours

Purpose. Amplification of genetic sequences on chromosome 12q13 is frequently found in soft tissue tumours. However, for the MDM2 gene, over-expression of the MDM2 protein has not always been shown to accompany gene amplification, raising the possibility that amplification of genetic sequences targe...

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Detalles Bibliográficos
Autores principales: Patterson, Helen, Barnes, Diana, Gill, Sandra, Spicer, James, Fisher, Cyril, Thomas, Merion, Grimer, Robert, Fletcher, Chris, Gusterson, Barry, Cooper, Colin
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 1997
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373578/
https://www.ncbi.nlm.nih.gov/pubmed/18521196
http://dx.doi.org/10.1080/13577149778434

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373578/
https://www.ncbi.nlm.nih.gov/pubmed/18521196
http://dx.doi.org/10.1080/13577149778434

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