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Hepatitis C Virus Diversity and Evolution in the Full Open-Reading Frame during Antiviral Therapy
BACKGROUND: Pegylated interferon plus ribavirin therapy for hepatitis C virus (HCV) fails in approximately half of genotype 1 patients. Treatment failure occurs either by nonresponse (minimal declines in viral titer) or relapse (robust initial responses followed by rebounds of viral titers during or...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373758/ https://www.ncbi.nlm.nih.gov/pubmed/18463735 http://dx.doi.org/10.1371/journal.pone.0002123 |