Cargando…

IL-6–dependent spontaneous proliferation is required for the induction of colitogenic IL-17–producing CD8(+) T cells

We propose a novel role for interleukin (IL) 6 in inducing rapid spontaneous proliferation (SP) of naive CD8(+) T cells, which is a crucial step in the differentiation of colitogenic CD8(+) T cells. Homeostasis of T cells is regulated by two distinct modes of cell proliferation: major histocompatibi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tajima, Masaki, Wakita, Daiko, Noguchi, Daisuke, Chamoto, Kenji, Yue, Zhang, Fugo, Kazunori, Ishigame, Harumichi, Iwakura, Yoichiro, Kitamura, Hidemitsu, Nishimura, Takashi
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2008
Materias:	Brief Definitive Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373835/ https://www.ncbi.nlm.nih.gov/pubmed/18426983 http://dx.doi.org/10.1084/jem.20071133

Ejemplares similares

IL-17-producing (©)™T cells are important for the development of arthritis in a rheumatoid arthritis model
por: Akitsu, Aoi, et al.
Publicado: (2012)

T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17(+) Th cells that cause autoimmune arthritis
por: Hirota, Keiji, et al.
Publicado: (2007)

IL-1 receptor antagonist-deficient mice develop autoimmune arthritis due to intrinsic activation of IL-17-producing CCR2(+)Vγ6(+)γδ T cells
por: Akitsu, Aoi, et al.
Publicado: (2015)

IL-36 cytokines imprint a colitogenic phenotype on CD4(+) T helper cells
por: Leon, Gemma, et al.
Publicado: (2022)

Colitogenic effector T cells: roles of gut homing integrin, gut antigen specificity, and γδ T cells
por: Do, Jeong-su, et al.
Publicado: (2013)

Commensal-dependent expression of IL-25 regulates the IL-23–IL-17 axis in the intestine
por: Zaph, Colby, et al.
Publicado: (2008)

Autoantibodies against IL-17A, IL-17F, and IL-22 in patients with chronic mucocutaneous candidiasis and autoimmune polyendocrine syndrome type I
por: Puel, Anne, et al.
Publicado: (2010)

Therapeutic targets for rheumatoid arthritis: lessons from animal models
por: Iwakura, Yoichiro, et al.
Publicado: (2012)

Lymphoid tissue inducer–like cells are an innate source of IL-17 and IL-22
por: Takatori, Hiroaki, et al.
Publicado: (2009)

Interleukin (IL)-22 and IL-17 are coexpressed by Th17 cells and cooperatively enhance expression of antimicrobial peptides
por: Liang, Spencer C., et al.
Publicado: (2006)

IL-17 can promote tumor growth through an IL-6–Stat3 signaling pathway
por: Wang, Lin, et al.
Publicado: (2009)

Mutations in STAT3 and IL12RB1 impair the development of human IL-17–producing T cells
por: de Beaucoudrey, Ludovic, et al.
Publicado: (2008)

A crucial role for interleukin (IL)-1 in the induction of IL-17–producing T cells that mediate autoimmune encephalomyelitis
por: Sutton, Caroline, et al.
Publicado: (2006)

Interleukin (IL)-4 inhibits IL-10 to promote IL-12 production by dendritic cells
por: Yao, Yongxue, et al.
Publicado: (2005)

Microbiota-induced IL-1β, but not IL-6, is critical for the development of steady-state T(H)17 cells in the intestine
por: Shaw, Michael H., et al.
Publicado: (2012)

Intestinal Colonization of IL-2 Deficient Mice with Non-Colitogenic B. vulgatus Prevents DC Maturation and T-Cell Polarization
por: Müller, Martina, et al.
Publicado: (2008)

Sodium Butyrate Reduces Colitogenic Immunoglobulin A-Coated Bacteria and Modifies the Composition of Microbiota in IL-10 Deficient Mice
por: Zhang, Tenghui, et al.
Publicado: (2016)

Neutrophils Are Essential As A Source Of Il-17 In The Effector Phase Of Arthritis
por: Katayama, Masaki, et al.
Publicado: (2013)

A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity
por: Terashima, Asuka, et al.
Publicado: (2008)

Arteriosclerosis Derived from Cutaneous Inflammation Is Ameliorated by the Deletion of IL-17A and IL-17F
por: Nakanishi, Takehisa, et al.
Publicado: (2023)

Correction: Neutrophils Are Essential As A Source Of Il-17 In The Effector Phase Of Arthritis
por: Katayama, Masaki, et al.
Publicado: (2013)

CD101 inhibits the expansion of colitogenic T cells
por: Schey, Regina, et al.
Publicado: (2016)

Surface-Associated Lipoproteins Link Enterococcus faecalis Virulence to Colitogenic Activity in IL-10-Deficient Mice Independent of Their Expression Levels
por: Ocvirk, Soeren, et al.
Publicado: (2015)

IL-17 produced by Paneth cells drives TNF-induced shock
por: Takahashi, Nozomi, et al.
Publicado: (2008)

Role of IL-17 and regulatory T lymphocytes in a systemic autoimmune disease
por: Lohr, Jens, et al.
Publicado: (2006)

IL-9 as a mediator of Th17-driven inflammatory disease
por: Nowak, Elizabeth C., et al.
Publicado: (2009)

Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation
por: Murphy, Craig A., et al.
Publicado: (2003)

IL-31–IL-31R interactions negatively regulate type 2 inflammation in the lung
por: Perrigoue, Jacqueline G., et al.
Publicado: (2007)

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells
por: Seddiki, Nabila, et al.
Publicado: (2006)

The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4(+) T cells
por: Dienz, Oliver, et al.
Publicado: (2009)

IL-33 reduces the development of atherosclerosis
por: Miller, Ashley M., et al.
Publicado: (2008)

Blimp-1 directly represses Il2 and the Il2 activator Fos, attenuating T cell proliferation and survival
por: Martins, Gislâine A., et al.
Publicado: (2008)

Inhibition of NK cell activity by IL-17 allows vaccinia virus to induce severe skin lesions in a mouse model of eczema vaccinatum
por: Kawakami, Yuko, et al.
Publicado: (2009)

Identification of novel helper epitopes of MAGE-A4 tumour antigen: useful tool for the propagation of Th1 cells
por: Ohkuri, T, et al.
Publicado: (2009)

Rag2-deficient IL-1 Receptor Antagonist-deficient Mice Are a Novel Colitis Model in Which Innate Lymphoid Cell-derived IL-17 Is Involved in the Pathogenesis
por: Akitsu, Aoi, et al.
Publicado: (2014)

Interleukin (IL)-4–independent Induction of Immunoglobulin (Ig)E, and Perturbation of T Cell Development in Transgenic Mice Expressing IL-13
por: Emson, Claire L., et al.
Publicado: (1998)

IL-17-producing γδ T cells enhance bone regeneration
por: Ono, Takehito, et al.
Publicado: (2016)

Local microbleeding facilitates IL-6– and IL-17–dependent arthritis in the absence of tissue antigen recognition by activated T cells
por: Murakami, Masaaki, et al.
Publicado: (2011)

Local microbleeding facilitates IL-6– and IL-17–dependent arthritis in the absence of tissue antigen recognition by activated T cells
por: Murakami, Masaaki, et al.
Publicado: (2012)

A late IL-33 response after exposure to Schistosoma haematobium antigen is associated with an up-regulation of IL-13 in human eosinophils
por: Wilson, S, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_u3ubu0knra2o66gg6q181coj4s