C5 deficiency and C5a or C5aR blockade protects against cerebral malaria

Experimental infection of mice with Plasmodium berghei ANKA (PbA) provides a powerful model to define genetic determinants that regulate the development of cerebral malaria (CM). Based on the hypothesis that excessive activation of the complement system may confer susceptibility to CM, we investigat...

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Detalles Bibliográficos
Autores principales: Patel, Samir N., Berghout, Joanne, Lovegrove, Fiona E., Ayi, Kodjo, Conroy, Andrea, Serghides, Lena, Min-oo, Gundula, Gowda, D. Channe, Sarma, J. Vidya, Rittirsch, Daniel, Ward, Peter A., Liles, W. Conrad, Gros, Philippe, Kain, Kevin C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373845/
https://www.ncbi.nlm.nih.gov/pubmed/18426986
http://dx.doi.org/10.1084/jem.20072248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373845/
https://www.ncbi.nlm.nih.gov/pubmed/18426986
http://dx.doi.org/10.1084/jem.20072248

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