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T cell receptor–instructed αβ versus γδ lineage commitment revealed by single-cell analysis
αβ and γδ T cell lineages develop in the thymus from a common precursor. It is unclear at which stage of development commitment to these lineages takes place and in which way T cell receptor signaling contributes to the process. Recently, it was demonstrated that strong TCR signals favor γδ lineage...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373848/ https://www.ncbi.nlm.nih.gov/pubmed/18443226 http://dx.doi.org/10.1084/jem.20072425 |