MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells

Like CD1d-restricted iNKT cells, mucosal-associated invariant T cells (MAITs) are “innate” T cells that express a canonical TCRα chain, have a memory phenotype, and rapidly secrete cytokines upon TCR ligation. Unlike iNKT cells, MAIT cells require the class Ib molecule MHC-related protein I (MR1), B...

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Detalles Bibliográficos
Autores principales: Huang, Shouxiong, Gilfillan, Susan, Kim, Sojung, Thompson, Bruce, Wang, Xiaoli, Sant, Andrea J., Fremont, Daved H., Lantz, Olivier, Hansen, Ted H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2008
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373850/
https://www.ncbi.nlm.nih.gov/pubmed/18443227
http://dx.doi.org/10.1084/jem.20072579

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