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ATF4 is an oxidative stress–inducible, prodeath transcription factor in neurons in vitro and in vivo
Oxidative stress is pathogenic in neurological diseases, including stroke. The identity of oxidative stress–inducible transcription factors and their role in propagating the death cascade are not well known. In an in vitro model of oxidative stress, the expression of the bZip transcription factor ac...
Autores principales: | Lange, Philipp S., Chavez, Juan C., Pinto, John T., Coppola, Giovanni, Sun, Chiao-Wang, Townes, Tim M., Geschwind, Daniel H., Ratan, Rajiv R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373852/ https://www.ncbi.nlm.nih.gov/pubmed/18458112 http://dx.doi.org/10.1084/jem.20071460 |
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