High Cyclin E Staining Index in Blastemal, Stromal or Epithelial Cells Is Correlated with Tumor Aggressiveness in Patients with Nephroblastoma

PURPOSE: Identifying among nephroblastoma those with a high propensity for distant metastases using cell cycle markers: cyclin E as a regulator of progression through the cell cycle and Ki-67 as a tumor proliferation marker, since both are often deregulated in many human malignancies. METHODOLOGY/PR...

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Detalles Bibliográficos
Autores principales: Berrebi, Dominique, Leclerc, Julie, Schleiermacher, Gudrun, Zaccaria, Isabelle, Boccon-Gibod, Liliane, Fabre, Monique, Jaubert, Francis, El Ghoneimi, Alaa, Jeanpierre, Cécile, Peuchmaur, Michel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373888/
https://www.ncbi.nlm.nih.gov/pubmed/18493303
http://dx.doi.org/10.1371/journal.pone.0002216

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