Does gene dosage really matter?

Mechanisms to compensate for dosage differences of genes on sex chromosomes are widespread in animals and have been thought to be critical for viability. However, in birds, compensation is inefficient, implying that for many genes dosage compensation is not critical, and for some genes, dosage diffe...

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Detalles Bibliográficos
Autores principales: Graves, Jennifer A Marshall, Disteche, Christine M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373895/
https://www.ncbi.nlm.nih.gov/pubmed/17381829
http://dx.doi.org/10.1186/jbiol55
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author Graves, Jennifer A Marshall
Disteche, Christine M
author_facet Graves, Jennifer A Marshall
Disteche, Christine M
author_sort Graves, Jennifer A Marshall
collection PubMed
description Mechanisms to compensate for dosage differences of genes on sex chromosomes are widespread in animals and have been thought to be critical for viability. However, in birds, compensation is inefficient, implying that for many genes dosage compensation is not critical, and for some genes, dosage differences have even been selected for.
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spelling pubmed-23738952008-05-09 Does gene dosage really matter? Graves, Jennifer A Marshall Disteche, Christine M J Biol Minireview Mechanisms to compensate for dosage differences of genes on sex chromosomes are widespread in animals and have been thought to be critical for viability. However, in birds, compensation is inefficient, implying that for many genes dosage compensation is not critical, and for some genes, dosage differences have even been selected for. BioMed Central 2007 2007-03-22 /pmc/articles/PMC2373895/ /pubmed/17381829 http://dx.doi.org/10.1186/jbiol55 Text en Copyright © 2007 BioMed Central Ltd
spellingShingle Minireview
Graves, Jennifer A Marshall
Disteche, Christine M
Does gene dosage really matter?
title Does gene dosage really matter?
title_full Does gene dosage really matter?
title_fullStr Does gene dosage really matter?
title_full_unstemmed Does gene dosage really matter?
title_short Does gene dosage really matter?
title_sort does gene dosage really matter?
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373895/
https://www.ncbi.nlm.nih.gov/pubmed/17381829
http://dx.doi.org/10.1186/jbiol55
work_keys_str_mv AT gravesjenniferamarshall doesgenedosagereallymatter
AT distechechristinem doesgenedosagereallymatter

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