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Efficacious Recombinant Influenza Vaccines Produced by High Yield Bacterial Expression: A Solution to Global Pandemic and Seasonal Needs

It is known that physical linkage of TLR ligands and vaccine antigens significantly enhances the immunopotency of the linked antigens. We have used this approach to generate novel influenza vaccines that fuse the globular head domain of the protective hemagglutinin (HA) antigen with the potent TLR5...

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Detalles Bibliográficos
Autores principales:	Song, Langzhou, Nakaar, Valerian, Kavita, Uma, Price, Albert, Huleatt, Jim, Tang, Jie, Jacobs, Andrea, Liu, Ge, Huang, Yan, Desai, Priyanka, Maksymiuk, Gail, Takahashi, Virginia, Umlauf, Scott, Reiserova, Lucia, Bell, Rodney, Li, Hong, Zhang, Yi, McDonald, William F., Powell, T. J., Tussey, Lynda
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373928/ https://www.ncbi.nlm.nih.gov/pubmed/18493310 http://dx.doi.org/10.1371/journal.pone.0002257

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