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Crystallization of hepatocyte nuclear factor 4α (HNF4α) in complex with the HNF1α promoter element
Hepatocyte nuclear factor 4α (HNF4α) is a member of the nuclear receptor superfamily that plays a central role in organ development and metabolic functions. Mutations on HNF4α cause maturity-onset diabetes of the young (MODY), a dominant monogenic cause of diabetes. In order to understand the molecu...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374247/ https://www.ncbi.nlm.nih.gov/pubmed/18391435 http://dx.doi.org/10.1107/S1744309108007136 |