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Crystallization of hepatocyte nuclear factor 4α (HNF4α) in complex with the HNF1α promoter element

Hepatocyte nuclear factor 4α (HNF4α) is a member of the nuclear receptor superfamily that plays a central role in organ development and metabolic functions. Mutations on HNF4α cause maturity-onset diabetes of the young (MODY), a dominant monogenic cause of diabetes. In order to understand the molecu...

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Detalles Bibliográficos
Autores principales:	Lu, Peng, Liu, Jianguo, Melikishvili, Manana, Fried, Michael G., Chi, Young-In
Formato:	Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2008
Materias:	Crystallization Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374247/ https://www.ncbi.nlm.nih.gov/pubmed/18391435 http://dx.doi.org/10.1107/S1744309108007136

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