DNA methylation analysis at distal and proximal promoter regions of the oestrogen receptor gene in breast cancers

Oestrogen receptor α (ER-α) gene has two specific promoters, distal (P0) and proximal (P1), which induce almost identical transcripts in size due to different splicing. We examined the methylation at both promoter regions of the ER-α gene using HpaII, a methylation-sensitive restriction enzyme, prio...

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Detalles Bibliográficos
Autores principales: Iwase, H, Omoto, Y, Iwata, H, Toyama, T, Hara, Y, Ando, Y, Ito, Y, Fujii, Y, Kobayashi, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374276/
https://www.ncbi.nlm.nih.gov/pubmed/10471050
http://dx.doi.org/10.1038/sj.bjc.6690631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374276/
https://www.ncbi.nlm.nih.gov/pubmed/10471050
http://dx.doi.org/10.1038/sj.bjc.6690631

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