Cargando…

DNA methylation analysis at distal and proximal promoter regions of the oestrogen receptor gene in breast cancers

Oestrogen receptor α (ER-α) gene has two specific promoters, distal (P0) and proximal (P1), which induce almost identical transcripts in size due to different splicing. We examined the methylation at both promoter regions of the ER-α gene using HpaII, a methylation-sensitive restriction enzyme, prio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iwase, H, Omoto, Y, Iwata, H, Toyama, T, Hara, Y, Ando, Y, Ito, Y, Fujii, Y, Kobayashi, S
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1999
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374276/ https://www.ncbi.nlm.nih.gov/pubmed/10471050 http://dx.doi.org/10.1038/sj.bjc.6690631

Ejemplares similares

Postmenopausal endogenous oestrogens and risk of endometrial cancer: results of a prospective study
por: Zeleniuch-Jacquotte, A, et al.
Publicado: (2001)

Dose escalation and pharmacokinetic study of a humanized anti-HER2 monoclonal antibody in patients with HER2/neu-overexpressing metastatic breast cancer
por: Tokuda, Y, et al.
Publicado: (1999)

The two phyto-oestrogens genistein and quercetin exert different effects on oestrogen receptor function
por: Miodini, P, et al.
Publicado: (1999)

Prognostic value of performance status assessed by patients themselves, nurses, and oncologists in advanced non-small cell lung cancer
por: Ando, M, et al.
Publicado: (2001)

Anti-HER2 antibody enhances the growth inhibitory effect of anti-oestrogen on breast cancer cells expressing both oestrogen receptors and HER2
por: Kunisue, H, et al.
Publicado: (2000)

Different methylation of oestrogen receptor DNA in human breast carcinomas with and without oestrogen receptor.
por: Piva, R., et al.
Publicado: (1990)

The DNA mismatch repair gene hMSH2 is a potent coactivator of oestrogen receptor α
por: Wada-Hiraike, O, et al.
Publicado: (2005)

Oestrogen-mediated cardioprotection following ischaemia and reperfusion is mimicked by an oestrogen receptor (ER)α agonist and unaffected by an ERβ antagonist
por: Jeanes, Helen L, et al.
Publicado: (2008)

Differential effects of cisplatin in proximal and distal renal tubule epithelial cell lines
por: Kröning, R, et al.
Publicado: (1999)

Oestrogen receptor β expression and depth of myometrial invasion in human endometrial cancer
por: Takama, F, et al.
Publicado: (2001)

Nuclear translocation of beta-catenin in colorectal cancer
por: Kobayashi, M, et al.
Publicado: (2000)

Hormonal therapy with megestrol in inoperable hepatocellular carcinoma characterized by variant oestrogen receptors
por: Villa, E, et al.
Publicado: (2001)

Alcohol consumption and breast cancer oestrogen and progesterone receptor status
por: Enger, S M, et al.
Publicado: (1999)

DNA polymerase delta interacting protein 3 facilitates the activation and maintenance of DNA damage checkpoint in response to replication stress
por: Zhang, Sufang, et al.
Publicado: (2022)

Expression of oestrogen and progesterone receptors in low-grade endometrial stromal sarcomas
por: Reich, O, et al.
Publicado: (2000)

Probing the link between oestrogen receptors and oesophageal cancer
por: Rashid, Farhan, et al.
Publicado: (2010)

Oestrogen inhibits resveratrol-induced post-translational modification of p53 and apoptosis in breast cancer cells
por: Zhang, S, et al.
Publicado: (2004)

Expression of oestrogen and progesterone receptors in gastric cancer: a flow cytometric study
por: Karat, D, et al.
Publicado: (1999)

Oestrogen receptor-α variant mRNA expression in primary human breast tumours and matched lymph node metastases
por: Leygue, E, et al.
Publicado: (1999)

Safety and immunogenicity of a booster dose of S-268019-b: Interim findings of a Phase 3, open-label clinical study in Japan
por: Sonoyama, Takuhiro, et al.
Publicado: (2023)

Effect of pravastatin on survival in patients with advanced hepatocellular carcinoma. A randomized controlled trial
por: Kawata, S, et al.
Publicado: (2001)

Ethinylestradiol is beneficial for postmenopausal patients with heavily pre-treated metastatic breast cancer after prior aromatase inhibitor treatment: a prospective study
por: Iwase, H, et al.
Publicado: (2013)

Detailed deletion mapping of chromosome band 14q32 in human neuroblastoma defines a 1.1-Mb region of common allelic loss
por: Hoshi, M, et al.
Publicado: (2000)

Metallothionein 1E mRNA is highly expressed in oestrogen receptor-negative human invasive ductal breast cancer
por: Jin, R, et al.
Publicado: (2000)

Loss of heterozygosity of the oestrogen receptor gene in breast cancer.
por: Iwase, H., et al.
Publicado: (1995)

Induction of apoptosis in myeloid leukaemic cells by ribozymes targeted against AML1/MTG8
por: Matsushita, H, et al.
Publicado: (1999)

Thrombospondin 2 expression is correlated with inhibition of angiogenesis and metastasis of colon cancer
por: Tokunaga, T, et al.
Publicado: (1999)

Prevalence and molecular characterization of porcine Picobirnavirus in piglets of North East Region of India
por: Kylla, H., et al.
Publicado: (2016)

Granulocyte, granulocyte–macrophage, and macrophage colony-stimulating factors can stimulate the invasive capacity of human lung cancer cells
por: Pei, X-H, et al.
Publicado: (1999)

Application of positron emission tomography imaging to cancer screening
por: Yasuda, S, et al.
Publicado: (2000)

Quantitative determination, by real-time reverse transcription polymerase chain reaction, of aromatase mRNA in invasive ductal carcinoma of the breast
por: Zhang, Zhenhuan, et al.
Publicado: (2003)

Expression of interleukin 6 (IL-6) correlates with oestrogen receptor in human breast carcinoma
por: Fontanini, G, et al.
Publicado: (1999)

DNA methylation of oestrogen-regulated enhancers defines endocrine sensitivity in breast cancer
por: Stone, Andrew, et al.
Publicado: (2015)

Abnormalities of the FHIT gene in human oral carcinogenesis
por: Tanimoto, K, et al.
Publicado: (2000)

The expression of p73 is increased in lung cancer, independent of p53 gene alteration
por: Tokuchi, Y, et al.
Publicado: (1999)

Thymidine phosphorylase/platelet-derived endothelial cell growth factor is upregulated in advanced solid types of gastric cancer
por: Yoshikawa, T, et al.
Publicado: (1999)

O(6)-methylguanine-DNA methyltransferase activity is associated with response to alkylating agent therapy and with MGMT promoter methylation in glioblastoma and anaplastic glioma
por: Bobola, Michael S., et al.
Publicado: (2014)

Steroid sulphatase and oestrogen sulphotransferase in human non-small-cell lung carcinoma
por: Iida, S, et al.
Publicado: (2013)

Tamoxifen induces oxidative stress and apoptosis in oestrogen receptor-negative human cancer cell lines
por: Ferlini, C, et al.
Publicado: (1999)

Decreasing of p27(Kip1) and cyclin E protein levels is associated with progression from superficial into invasive bladder cancer
por: Kamai, T, et al.
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_j49q7lb3is5ghke7sfkmdlge2a