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Evaluation of rodent-only toxicology for early clinical trials with novel cancer therapeutics
Preclinical toxicology studies are performed prior to phase I trials with novel cancer therapeutics to identify a safe clinical starting dose and potential human toxicities. The primary aim of this study was to evaluate the ability of rodent-only toxicology studies to identify a safe phase I trial s...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
1999
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374299/ https://www.ncbi.nlm.nih.gov/pubmed/10555743 http://dx.doi.org/10.1038/sj.bjc.6690761 |