Lack of MHC class I surface expression on neoplastic cells and poor activation of the secretory pathway of cytotoxic cells in oral squamous cell carcinomas

Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells use the secretory pathway of perforin/granzymes to kill their target cells. In contrast to NK cells, CTL responses are MHC class I restricted. In this study we analysed the relative activation of CTL and NK cells in relation with MHC class...

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Detalles Bibliográficos
Autores principales: Cruz, I, Meijer, C J L M, Walboomers, J M M, Snijders, P J F, Waal, I Van der
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374311/
https://www.ncbi.nlm.nih.gov/pubmed/10555762
http://dx.doi.org/10.1038/sj.bjc.6690780

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