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Suppression of the c-erbB-2 gene product decreases transformation abilities but not the proliferation and secretion of proteases of SK-OV-3 ovarian cancer cells

The overexpression of the c-erbB-2 oncogene product has been reported in approximately 20–30% of human ovarian cancers and has been correlated with a poor prognosis in ovarian cancer patients. To investigate the function of p185(c-erbB-2) in human ovarian cancer cells, a c-erbB-2-specific single-cha...

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Detalles Bibliográficos
Autores principales: Wiechen, K, Karaaslan, S, Turzynski, A, Dietel, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374312/
https://www.ncbi.nlm.nih.gov/pubmed/10555747
http://dx.doi.org/10.1038/sj.bjc.6690765

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