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Human germ cell tumours: expression of γ-glutamyl transpeptidase and sensitivity to cisplatin
Previous studies have shown that the enzyme γ-glutamyl transpeptidase (GGT) is essential for the nephrotoxicity of cisplatin. This study was designed to determine whether GGT activity is necessary for the therapeutic effect of the drug. The relationship between GGT expression and clinical response t...
Autores principales: | Hanigan, M H, Frierson, H F, Abeler, V M, Kaern, J, Taylor, P T |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374348/ https://www.ncbi.nlm.nih.gov/pubmed/10487615 http://dx.doi.org/10.1038/sj.bjc.6690653 |
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