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Primary response of the sGC heme binding domain to the cleavage of the Fe-His bond

Soluble guanylate cyclase (sGC) is an important heme sensor protein. Regulation of the status of heme in the heme binding domain (or HNOX domain) by various gaseous activators can increase the catalytic efficiency of the cyclase domain. Several studies have demonstrated that the full activation of s...

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Detalles Bibliográficos
Autores principales: Zhang, Huali, Lu, Ming, Zhang, Yuebin, Li, Zhengqiang
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374373/
https://www.ncbi.nlm.nih.gov/pubmed/18478082