Role of thymine in protein coding frames of mRNA sequences

Distribution of thymine in protein coding mRNA sequences has been studied here. Our study suggest that thymine in protein coding sequences are not randomly distributed but with probability. Frame1 prefers to have definite amount of thymine. It is observed that the thymine content of frame 4 is also...

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Autores principales: Anandagopu, Perumal, Suhanya, Sivakumar, Jayaraj, Veerasamy, Rajasekaran, Ekambaram
Formato: Texto
Lenguaje:English
Publicado: Biomedical Informatics Publishing Group 2008
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374375/
https://www.ncbi.nlm.nih.gov/pubmed/18478084
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author Anandagopu, Perumal
Suhanya, Sivakumar
Jayaraj, Veerasamy
Rajasekaran, Ekambaram
author_facet Anandagopu, Perumal
Suhanya, Sivakumar
Jayaraj, Veerasamy
Rajasekaran, Ekambaram
author_sort Anandagopu, Perumal
collection PubMed
description Distribution of thymine in protein coding mRNA sequences has been studied here. Our study suggest that thymine in protein coding sequences are not randomly distributed but with probability. Frame1 prefers to have definite amount of thymine. It is observed that the thymine content of frame 4 is also involved in protein coding. Frame 3 prefers to have least amount of thymine. However, frame 2 and frame 6 shows a variable degree of thymine content. The mRNA sequences of heterosexual animals, particularly, the human show a different distribution profile (less thymine in frame 1) compared to that of yeast and plants.
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spelling pubmed-23743752008-05-13 Role of thymine in protein coding frames of mRNA sequences Anandagopu, Perumal Suhanya, Sivakumar Jayaraj, Veerasamy Rajasekaran, Ekambaram Bioinformation Hypothesis Distribution of thymine in protein coding mRNA sequences has been studied here. Our study suggest that thymine in protein coding sequences are not randomly distributed but with probability. Frame1 prefers to have definite amount of thymine. It is observed that the thymine content of frame 4 is also involved in protein coding. Frame 3 prefers to have least amount of thymine. However, frame 2 and frame 6 shows a variable degree of thymine content. The mRNA sequences of heterosexual animals, particularly, the human show a different distribution profile (less thymine in frame 1) compared to that of yeast and plants. Biomedical Informatics Publishing Group 2008-04-19 /pmc/articles/PMC2374375/ /pubmed/18478084 Text en © 2008 Biomedical Informatics Publishing Group This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
spellingShingle Hypothesis
Anandagopu, Perumal
Suhanya, Sivakumar
Jayaraj, Veerasamy
Rajasekaran, Ekambaram
Role of thymine in protein coding frames of mRNA sequences
title Role of thymine in protein coding frames of mRNA sequences
title_full Role of thymine in protein coding frames of mRNA sequences
title_fullStr Role of thymine in protein coding frames of mRNA sequences
title_full_unstemmed Role of thymine in protein coding frames of mRNA sequences
title_short Role of thymine in protein coding frames of mRNA sequences
title_sort role of thymine in protein coding frames of mrna sequences
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374375/
https://www.ncbi.nlm.nih.gov/pubmed/18478084
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AT jayarajveerasamy roleofthymineinproteincodingframesofmrnasequences
AT rajasekaranekambaram roleofthymineinproteincodingframesofmrnasequences

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