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Tumour necrosis factor alpha increases melphalan concentration in tumour tissue after isolated limb perfusion
Several possible mechanisms for the synergistic anti-tumour effects between tumour necrosis factor alpha (TNF-α) and melphalan after isolated limb perfusion (ILP) have been presented. We found a significant sixfold increase in melphalan tumour tissue concentration after ILP when TNF-α was added to t...
Autores principales: | de Wilt, J H W, ten Hagen, T L M, de Boeck, G, van Tiel, S T, de Bruijn, E A, Eggermont, A M M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374420/ https://www.ncbi.nlm.nih.gov/pubmed/10737379 http://dx.doi.org/10.1054/bjoc.1999.1032 |
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