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Common interleukin-6 promoter variants associate with the more severe forms of distal interphalangeal osteoarthritis

INTRODUCTION: The objective of this study was to investigate the relationship of the IL-6 promoter variants G-597A, G-572C and G-174C (rs1800797, rs1800796 and rs1800795, respectively), which have been shown to affect both the transcription and secretion of IL-6, to symptomatic distal interphalangea...

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Detalles Bibliográficos
Autores principales:	Kämäräinen, Olli-Pekka, Solovieva, Svetlana, Vehmas, Tapio, Luoma, Katariina, Riihimäki, Hilkka, Ala-Kokko, Leena, Männikkö, Minna, Leino-Arjas, Päivi
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374458/ https://www.ncbi.nlm.nih.gov/pubmed/18257935 http://dx.doi.org/10.1186/ar2374

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