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Direct activation of oestrogen receptor- α by interleukin-6 in primary cultures of breast cancer epithelial cells
Interleukin 6 (IL-6) is secreted by breast tumours and shows synergistic activity with 17β-oestradiol (E2), leading to increases in reductive 17β-hydroxysteroid dehydrogenase activity in breast cancer epithelial cells. However, the mechanisms involved are poorly understood. Using short-term epitheli...
Autores principales: | Speirs, V, Kerin, M J, Walton, D S, Newton, C J, Desai, S B, Atkin, S L |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374478/ https://www.ncbi.nlm.nih.gov/pubmed/10755407 http://dx.doi.org/10.1054/bjoc.1999.1097 |
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