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Molecular analysis of the BRCA1 and BRCA2 genes in 32 breast and/or ovarian cancer Spanish families
It is estimated that about 5–10% of breast cancer cases may be due to inherited predisposition. Until now, two main susceptibility genes have been identified: BRCA1 and BRCA2. The first linkage and mutational studies suggested that mutations in these two genes would account for the majority of high-...
Autores principales: | Osorio, A, Barroso, A, Martínez, B, Cebrián, A, Román, J M San, Lobo, F, Robledo, M, Benítez, J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374482/ https://www.ncbi.nlm.nih.gov/pubmed/10755399 http://dx.doi.org/10.1054/bjoc.1999.1089 |
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