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Inhibition of radiation-induced apoptosis by dexamethasone in cervical carcinoma cell lines depends upon increased HPV E6/E7

Through a glucocorticoid-responsive promoter, glucocorticoids can regulate the transcription of the human papillomavirus (HPV) E6 and E7 viral genes which target the tumour suppressor proteins p53 and Rb respectively. In C4-1 cells, the glucocorticoid dexamethasone up-regulated HPV E6/E7 mRNA and de...

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Detalles Bibliográficos
Autores principales:	Kamradt, M C, Mohideen, N, Krueger, E, Walter, S, Vaughan, A T M
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2000
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374500/ https://www.ncbi.nlm.nih.gov/pubmed/10817508 http://dx.doi.org/10.1054/bjoc.2000.1114

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