Isolation and characterization of an IGROV-1 human ovarian cancer cell line made resistant to Ecteinascidin-743 (ET-743)

By exposing Igrov-1 human ovarian cancer cells to increasing concentrations of Ecteinascidin-743 (ET-743), either for a short or prolonged time, we obtained sublines resistant to ET-743 which overexpress Pgp. The most resistant clone (Igrov-1/25 ET) was evaluated for biological and pharmacological c...

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Detalles Bibliográficos
Autores principales: Erba, E, Bergamaschi, D, Bassano, L, Ronzoni, S, Liberti, G Di, Muradore, I, Vignati, S, Faircloth, G, Jimeno, J, D'Incalci, M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374505/
https://www.ncbi.nlm.nih.gov/pubmed/10817511
http://dx.doi.org/10.1054/bjoc.2000.1224

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374505/
https://www.ncbi.nlm.nih.gov/pubmed/10817511
http://dx.doi.org/10.1054/bjoc.2000.1224

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