Polymorphisms in GSTM1, GSTT1 and CYP1A1 and risk of pancreatic adenocarcinoma

A prospective study of 149 unselected incident cases of pancreatic adenocarcinoma and 146 ethnically-matched controls found no associations between GSTM1 (adjusted odds ratio (AOR) 1.14), GSTT1 (AOR: 1.19) and CYP1A1 (AOR: 1.08) polymorphisms and pancreatic cancer susceptibility. Smoking and drinkin...

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Autores principales: Liu, G, Ghadirian, P, Vesprini, D, Hamel, N, Paradis, A-J, Lal, G, Gallinger, S, Narod, S A, Foulkes, W D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374522/
https://www.ncbi.nlm.nih.gov/pubmed/10817498
http://dx.doi.org/10.1054/bjoc.2000.1221
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author Liu, G
Ghadirian, P
Vesprini, D
Hamel, N
Paradis, A-J
Lal, G
Gallinger, S
Narod, S A
Foulkes, W D
author_facet Liu, G
Ghadirian, P
Vesprini, D
Hamel, N
Paradis, A-J
Lal, G
Gallinger, S
Narod, S A
Foulkes, W D
author_sort Liu, G
collection PubMed
description A prospective study of 149 unselected incident cases of pancreatic adenocarcinoma and 146 ethnically-matched controls found no associations between GSTM1 (adjusted odds ratio (AOR) 1.14), GSTT1 (AOR: 1.19) and CYP1A1 (AOR: 1.08) polymorphisms and pancreatic cancer susceptibility. Smoking and drinking status did not affect results. These polymorphisms do not appear to be important gene modifiers in pancreatic cancer. © 2000 Cancer Research Campaign
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spelling pubmed-23745222009-09-10 Polymorphisms in GSTM1, GSTT1 and CYP1A1 and risk of pancreatic adenocarcinoma Liu, G Ghadirian, P Vesprini, D Hamel, N Paradis, A-J Lal, G Gallinger, S Narod, S A Foulkes, W D Br J Cancer Regular Article A prospective study of 149 unselected incident cases of pancreatic adenocarcinoma and 146 ethnically-matched controls found no associations between GSTM1 (adjusted odds ratio (AOR) 1.14), GSTT1 (AOR: 1.19) and CYP1A1 (AOR: 1.08) polymorphisms and pancreatic cancer susceptibility. Smoking and drinking status did not affect results. These polymorphisms do not appear to be important gene modifiers in pancreatic cancer. © 2000 Cancer Research Campaign Nature Publishing Group 2000-05 2000-04-27 /pmc/articles/PMC2374522/ /pubmed/10817498 http://dx.doi.org/10.1054/bjoc.2000.1221 Text en Copyright © 2000 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Regular Article
Liu, G
Ghadirian, P
Vesprini, D
Hamel, N
Paradis, A-J
Lal, G
Gallinger, S
Narod, S A
Foulkes, W D
Polymorphisms in GSTM1, GSTT1 and CYP1A1 and risk of pancreatic adenocarcinoma
title Polymorphisms in GSTM1, GSTT1 and CYP1A1 and risk of pancreatic adenocarcinoma
title_full Polymorphisms in GSTM1, GSTT1 and CYP1A1 and risk of pancreatic adenocarcinoma
title_fullStr Polymorphisms in GSTM1, GSTT1 and CYP1A1 and risk of pancreatic adenocarcinoma
title_full_unstemmed Polymorphisms in GSTM1, GSTT1 and CYP1A1 and risk of pancreatic adenocarcinoma
title_short Polymorphisms in GSTM1, GSTT1 and CYP1A1 and risk of pancreatic adenocarcinoma
title_sort polymorphisms in gstm1, gstt1 and cyp1a1 and risk of pancreatic adenocarcinoma
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374522/
https://www.ncbi.nlm.nih.gov/pubmed/10817498
http://dx.doi.org/10.1054/bjoc.2000.1221
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