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A phase I and pharmacokinetic study of the combination of capecitabine and docetaxel in patients with advanced solid tumours
Capecitabine and docetaxel are both active against a variety of solid tumours, while their toxicity profiles only partly overlap. This phase I study was performed to determine the maximum tolerated dose (MTD) and side-effects of the combination, and to establish whether there is any pharmacokinetic...
Autores principales: | Pronk, L C, Vasey, P, Sparreboom, A, Reigner, B, Planting, A S Th, Gordon, R J, Osterwalder, B, Verweij, J, Twelves, C |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374547/ https://www.ncbi.nlm.nih.gov/pubmed/10883663 http://dx.doi.org/10.1054/bjoc.2000.1160 |
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