Risk of ovarian cancer in relation to use of phenolphthalein-containing laxatives

We examined ovarian cancer risk in relation to use of phenolphthalein-containing laxatives in 410 epithelial ovarian cancer cases and 713 controls. Compared to women who never used a laxative, ever use of a phenolphthalein-containing laxative was not associated with an increased risk of ovarian canc...

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Detalles Bibliográficos
Autores principales: Cooper, G S, Longnecker, M P, Sandler, D P, Ness, R B
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374557/
https://www.ncbi.nlm.nih.gov/pubmed/10917559
http://dx.doi.org/10.1054/bjoc.2000.1250
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author Cooper, G S
Longnecker, M P
Sandler, D P
Ness, R B
author_facet Cooper, G S
Longnecker, M P
Sandler, D P
Ness, R B
author_sort Cooper, G S
collection PubMed
description We examined ovarian cancer risk in relation to use of phenolphthalein-containing laxatives in 410 epithelial ovarian cancer cases and 713 controls. Compared to women who never used a laxative, ever use of a phenolphthalein-containing laxative was not associated with an increased risk of ovarian cancer (odds ratio, OR, 1.1, 95% confidence interval, CI, 0.9–1.4). Risk was slightly, but not significantly, higher with more frequent use (OR 1.2 for 75 or more days of use). When women who used non-phenolphthalein containing laxatives was used as the reference group, the associations were slightly, but not significantly larger (OR 1.4 for any use of phenolphthalein-containing laxatives and OR 1.5 for 75 or more days of use) © 2000 Cancer Research Campaign
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spelling pubmed-23745572009-09-10 Risk of ovarian cancer in relation to use of phenolphthalein-containing laxatives Cooper, G S Longnecker, M P Sandler, D P Ness, R B Br J Cancer Regular Article We examined ovarian cancer risk in relation to use of phenolphthalein-containing laxatives in 410 epithelial ovarian cancer cases and 713 controls. Compared to women who never used a laxative, ever use of a phenolphthalein-containing laxative was not associated with an increased risk of ovarian cancer (odds ratio, OR, 1.1, 95% confidence interval, CI, 0.9–1.4). Risk was slightly, but not significantly, higher with more frequent use (OR 1.2 for 75 or more days of use). When women who used non-phenolphthalein containing laxatives was used as the reference group, the associations were slightly, but not significantly larger (OR 1.4 for any use of phenolphthalein-containing laxatives and OR 1.5 for 75 or more days of use) © 2000 Cancer Research Campaign Nature Publishing Group 2000-07 2000-07-03 /pmc/articles/PMC2374557/ /pubmed/10917559 http://dx.doi.org/10.1054/bjoc.2000.1250 Text en Copyright © 2000 Cancer Research Campaign https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Regular Article
Cooper, G S
Longnecker, M P
Sandler, D P
Ness, R B
Risk of ovarian cancer in relation to use of phenolphthalein-containing laxatives
title Risk of ovarian cancer in relation to use of phenolphthalein-containing laxatives
title_full Risk of ovarian cancer in relation to use of phenolphthalein-containing laxatives
title_fullStr Risk of ovarian cancer in relation to use of phenolphthalein-containing laxatives
title_full_unstemmed Risk of ovarian cancer in relation to use of phenolphthalein-containing laxatives
title_short Risk of ovarian cancer in relation to use of phenolphthalein-containing laxatives
title_sort risk of ovarian cancer in relation to use of phenolphthalein-containing laxatives
topic Regular Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374557/
https://www.ncbi.nlm.nih.gov/pubmed/10917559
http://dx.doi.org/10.1054/bjoc.2000.1250
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