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Tumour cell thrombospondin-1 regulates tumour cell adhesion and invasion through the urokinase plasminogen activator receptor

We have previously shown that platelet-produced thrombospondin-1 up-regulates the urokinase plasminogen activator and its receptor and promotes tumour cell invasion. Although tumour cells produce thrombospondin-1 in vivo, they produce only minimal amounts of thrombospondin-1 in vitro. To determine t...

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Detalles Bibliográficos
Autores principales: Albo, D, Rothman, V L, Roberts, D D, Tuszynski, G P
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374573/
https://www.ncbi.nlm.nih.gov/pubmed/10917542
http://dx.doi.org/10.1054/bjoc.2000.1268