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Are platelets a 'forgotten' source of sepsis-induced myocardial depressing factor(s)?
The mechanism of sepsis-induced cardiac failure was initially thought to be related to the presence of 'myocardial depressant' substances that directly alter heart function. Exosomes released by platelets and identified in the plasma are suggested to, at least partially, explain myocardial...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374606/ https://www.ncbi.nlm.nih.gov/pubmed/18254931 http://dx.doi.org/10.1186/cc6220 |
| _version_ | 1782154493120479232 |
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| author | Mebazaa, Alexandre |
| author_facet | Mebazaa, Alexandre |
| author_sort | Mebazaa, Alexandre |
| collection | PubMed |
| description | The mechanism of sepsis-induced cardiac failure was initially thought to be related to the presence of 'myocardial depressant' substances that directly alter heart function. Exosomes released by platelets and identified in the plasma are suggested to, at least partially, explain myocardial depression in sepsis. This hypothesis needs to be evaluated by clinical studies. |
| format | Text |
| id | pubmed-2374606 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2008 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-23746062008-05-09 Are platelets a 'forgotten' source of sepsis-induced myocardial depressing factor(s)? Mebazaa, Alexandre Crit Care Commentary The mechanism of sepsis-induced cardiac failure was initially thought to be related to the presence of 'myocardial depressant' substances that directly alter heart function. Exosomes released by platelets and identified in the plasma are suggested to, at least partially, explain myocardial depression in sepsis. This hypothesis needs to be evaluated by clinical studies. BioMed Central 2008 2008-01-23 /pmc/articles/PMC2374606/ /pubmed/18254931 http://dx.doi.org/10.1186/cc6220 Text en Copyright © 2008 BioMed Central Ltd |
| spellingShingle | Commentary Mebazaa, Alexandre Are platelets a 'forgotten' source of sepsis-induced myocardial depressing factor(s)? |
| title | Are platelets a 'forgotten' source of sepsis-induced myocardial depressing factor(s)? |
| title_full | Are platelets a 'forgotten' source of sepsis-induced myocardial depressing factor(s)? |
| title_fullStr | Are platelets a 'forgotten' source of sepsis-induced myocardial depressing factor(s)? |
| title_full_unstemmed | Are platelets a 'forgotten' source of sepsis-induced myocardial depressing factor(s)? |
| title_short | Are platelets a 'forgotten' source of sepsis-induced myocardial depressing factor(s)? |
| title_sort | are platelets a 'forgotten' source of sepsis-induced myocardial depressing factor(s)? |
| topic | Commentary |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374606/ https://www.ncbi.nlm.nih.gov/pubmed/18254931 http://dx.doi.org/10.1186/cc6220 |
| work_keys_str_mv | AT mebazaaalexandre areplateletsaforgottensourceofsepsisinducedmyocardialdepressingfactors |