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Restoring normoglycaemia: not so harmless

Three independent studies of tight glucose control were recently stopped prematurely due to an excess mortality in the intensive treatment arm. This commentary briefly discusses the potential mechanisms and reminds the potential benefits of physiological stress hyperglycemia.

Detalles Bibliográficos
Autor principal: Preiser, Jean-Charles
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374622/
https://www.ncbi.nlm.nih.gov/pubmed/18341709
http://dx.doi.org/10.1186/cc6787
Descripción
Sumario:Three independent studies of tight glucose control were recently stopped prematurely due to an excess mortality in the intensive treatment arm. This commentary briefly discusses the potential mechanisms and reminds the potential benefits of physiological stress hyperglycemia.