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Decreased DNA-PK activity in human cancer cells exhibiting hypersensitivity to low-dose irradiation

Low-dose hyper-radiosensitivity (HRS) (below 0.5 Gy) has been extensively documented in the past few years. The molecular basis of this phenomenon remains largely unknown and the purpose of this study was to investigate the possible implication of the DNA repair DNA-PK complex. The activity of the D...

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Detalles Bibliográficos
Autores principales: Vaganay-Juéry, S, Muller, C, Marangoni, E, Abdulkarim, B, Deutsch, E, Lambin, P, Calsou, P, Eschwege, F, Salles, B, Joiner, M, Bourhis, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2374662/
https://www.ncbi.nlm.nih.gov/pubmed/10945500
http://dx.doi.org/10.1054/bjoc.2000.1258